The mitotic spindle checkpoint
نویسنده
چکیده
One of the most awe-inspiring demonstrations in biology is a timelapse video of mitosis viewed with high magnification phase contrast or Nomarski DIC microscopy. From initial chaotic movement comes the orderly alignment of chromosomes at the metaphase plate followed by a flawlessly synchronous splitting of the chromosomes and their gliding separation to the two mitotic poles. Enforcing the timing and synchrony of chromosome segregation is the job of the spindle checkpoint.
منابع مشابه
Spatio-temporal Model for Silencing of the Mitotic Spindle Assembly Checkpoint
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عنوان ژورنال:
- Current Biology
دوره 11 شماره
صفحات -
تاریخ انتشار 2001